Purpose: Acute lymphoblastic leukemia (ALL) is the most common type of cancer diagnosed in children.Despite cure rates of higher than 85 %, refractory or relapsed ALL still exhibits a bleak prognosis indicative of the dearth of treatment modalities specific for relapsed or refractory ALL.Prior research has implicated metabolic alterations in leukem
Abstract This Critical Synthesis Package contains: (1) a Critical Analysis of the psychometric properties and the application to health sciences education of the Seasonal Pattern Assessment Questionnaire (SPAQ), and (2) a copy of the instrument developed by Norman Rosenthal, MD.The SPAQ is a brief, self-administered screening tool for seasonal dadd
Background: Understanding how the elderly in developing countries spend their time has received little attention.Moreover, the potential of time use data to discern variation in activity patterns has not been fully realized by methods australis palette which use a mean added time approach.Objective: To uncover patterns of time use among the elderly
Abstract The advent of whole genome sequencing has revealed that common laboratory strains of human cytomegalovirus (HCMV) have major genetic deficiencies resulting from serial passage in fibroblasts.In particular, tropism for epithelial and endothelial cells is lost due to mutations disrupting genes UL128, UL130, or UL131A, which encode subunits o